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(2017) 22(2):e12376

PMID: 27801522 www.ncbi.nlm.nih.gov/pubmed/27801522

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In a , the curves represent the mean of n = 3 biologically independent experiments (except for PMB on the left, and peptide 4 (0.8 g ml 1 ), for which n = 2 biologically independent experiments)

These M1 cells make crown structures and release TNF-, IL-1, and IL-6 (144, 145)

However, once they surpass their physiological concentrations, ROS subject cells to oxidative stress and viciously interact with cellular proteins, carbohydrates, nucleic acid, and lipids, resulting in DNA and protein damage and lipid peroxidation [24] (Fig