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As an example, GSH depletion has been shown to promote pro-inflammatory microglial phenotypes and amplify astrocyte-microglia crosstalk (Vilhardt et al., 2017)

Bonner A, Walsh A, Shue J, Morton G, Fulmer T

Notably, KD appears to facilitate a more rapid reversal of renal function and molecular alterations compared to morphological changes [8]

doi: 10.1006/abbi.1999.1477

Since 17estradiol and relative compounds regulate various processes occurring in humans, inactivation of these compounds by the SULT1E1 enzyme constitute an important step in the prevention and development of certain diseases

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