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Recent studies suggest that SIRT1 plays a key role in regulating ferroptosis through multiple mechanisms, including the activation of nuclear factor erythroid 2-related factor 2 (NRF2), a master regulator of antioxidant defense [9]
Inflammaging is associated with an increase in pro-inflammatory markers and a decrease in anti-inflammatory markers in the body

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Other than the BBB, various barriers are also involved to protect the brain from hazardous elements
