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doi: 10.3390/ijms26136310

Mangiferin directly binds to Keap1, activates the downstream Nrf2/SLC7A11/GPX4 pathway, inhibits osteoblast ferroptosis, promotes bone formation and improves osteoporosis in ovariectomized mice and iron overload mice

recycles and extends the life spans of vitamin C, glutathione, and coenzyme Q10, all of which are needed for glutathione recycling

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