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MOTS-c half-life is approximately 2 to 4 hours, but the downstream cellular effects (mitochondrial biogenesis, gene expression changes) persist well beyond serum clearance

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The number of animals or wells used per experiment are indicated in the corresponding figures

doi:10.1164/rccm.201601-0088OC Qureshi WT, Nasir UB, Alqalyoobi S, et al

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