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The concept of long-term stores is a simplification that overlooks the rapid metabolic turnover and the fact that a symptomatic patient may experience a swift decline in their well-being as the effects of the last injection wane

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MIP-1 showed the highest sensitivity (92.2%) for identifying diseased study patients from controls

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However, immunoassays for measurement of 8-OHdG and F2-isoP have been criticized, although results employing this technology being widely published