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In the final rounds of refinement for both models, ordered solvent molecules and ligands were added and Translation-Libration-Screw (TLS) refinement (Winn et al, 2001) was employed

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This imbalance leads to a reduction in antioxidant enzyme levels, an increase in ROS levels, oxidative stress, and potentially cell death.Singh et al
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Thus, the reference intervals established in this study provide valuable guidance for clinical practice

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