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Physiol Plant 74(4):727732
++ = moderate
Researchers used a chemogenetic strategy to activate PV neurons and found that this significantly improved learning speed and perceptual learning ability in Fmr1 knockout mice (73)

They also have a significant impact on promoting communication between neurons and microglia

By restoring proper Treg function through targeted delivery of NAEis bound as protein drug conjugates to fusion proteins of IL-2 or anti-CD25 mAbs, we can re-establish immune tolerance without broad immunosuppression
