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Certain populations, including the elderly, vegetarians, and those with gastrointestinal disorders, may be at a higher risk of deficiency due to inadequate dietary intake or absorption issues

For example, hippocampus, amygdala, and cerebellar granule cells have been reported as the most susceptible to oxidative stress in some studies (Wang and Michaelis, 2010), and consequently are purported to be the first to undergo functional decline

In addition to the final rule, which adds six ingredients to the positive list and excludes four others, compounders must also be aware of the interim guidance for other ingredients that have been nominated for the 503A Bulk Substances List

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Some studies suggest BPC-157 may be useful for traumatic brain injuries (TBI) or stroke recovery, though more research is needed in these areas