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SIRT1 was immunoprecipitated and the level of NQO1 was examined by immunoblotting with NQO1 specific antibody (Fig 1E)

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As for MTs, the activity of zinc transporters, which transport zinc from the cytosol to the extracellular space or sequester zinc in intracellular compartments, contributes to zinc buffering, allowing the cell to store zinc and rapidly release it when needed temporarily

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