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Mnch et al., 2015)

Expression vectors were: pLVshCtrl (Sigma, SHC002), pLVshSTARD7#2 (Sigma, TRCN000028081), pLVshSTARD7#4 (Sigma, TRCN0000155648)

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It has been proven that intra-articular injections of statin during the development of OA reduced inflammatory cell infiltration and the expression of matrix-degrading enzymes, hence limiting cartilage deterioration (157)

8), and its structural analogs are among the very few highly potent inhibitors of the ALDH2 isozyme (IC 50 , 80 nM) (Lowe et al., 2008)

Catechins activate antioxidant enzymes, and the antioxidant power of human plasma increases with the continued intake of green tea