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Bortezomib is a proteasome inhibitor used as a first-line treatment for multiple myeloma, a type of blood cancer characterized by excessive proteasome activity
Most of these microorganisms are bacteria but also include fungi, viruses, and protozoa (a type of parasite)
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Dimopoulos M, Bringhen S, Anttila P, et al
The central mechanism of ferroptosis involves radical chain-mediated autoxidation (lipid peroxidation) of polyunsaturated fatty acid containing phospholipids (PUFA-PLs) to form high levels of cellular lipid hydroperoxides (PUFA-OOH, Figure 1A ) (3, 14)
