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Three mechanistic explanations, not mutually exclusive: Signalling cascade persistence: BPC-157 activates VEGFR2 and FAK-paxillin pathways whose downstream effects (angiogenesis, fibroblast migration, collagen remodelling) unfold over days to weeks after initial receptor engagement

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It is not best suited for severe osteoarthritis, advanced cartilage loss, major joint deformity, complete tendon rupture, fracture, or injuries requiring surgical evaluation

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(2018) Comprehensive overview of peptide bioregulators, including BPC derivatives and their biological significance in regeneration research

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Evidence suggests it may promote neuroprotection, regulate inflammation, and influence mood and cognition, with potential clinical relevance for neurodegenerative and psychiatric disorders

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