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The matrix metalloproteinase (MMP) family consists of zinc-dependent endopeptidases that play a vital role in degrading the ECM

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A.LiN.BauerD.MendoncaP.TakaE.DarbM.et al (2016)

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By the twenty-first century, the incidence stabilized in many early industrialized regions, except in children, in whom it continues to rise, whereas the prevalence of IBD continued to climb steadily across all age groups 4,8