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2005 Aug;37(8):1727-37

Subcutaneous Drug Injection Review (PMC) Pharmacologic considerations of the subcutaneous route for drug delivery

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Tolerance MYDAYIS may produce tolerance

But involved in metabolism is not the same as causes fat loss when injected. No large, well-designed randomised trial has demonstrated that MIC shots produce clinically meaningful weight loss

Skin concerns: Uneven body tone, post-friction darkening on knees and elbows, dullness, and loss of radiance over time