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Lade, S

In vitro studies on fibroblasts of PD patients have shown that CoQ10 intake restores the electron transport chain activity

J Clin Pharmacol 58:158167

10.1016/j.ygeno.2010.10.001 112 ShimaokaT.MiyakeC.YokotaA

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However, in GDH 1 knock-out mice (only humans express GDH 2) most functions, except the already mentioned reduced glutamate oxidation in cultured astrocytes, are remarkably intact (Frigerio et al., Table 2 Oxygen consumption rates as indications of kinetics of glutamate-dehydrogenase and aspartateglutamate transferase activities in non-synaptic mitochondria from the rat