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If you skip the 2mg phase entirely and start at 4mg (which some protocols allow), the gastrointestinal side effects are notably more severe, trading impatience now for discomfort later
Copper transporter 1 (CTR1) expression by mouse testicular germ cells, but not Sertoli cells, is essential for functional spermatogenesis

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doi: 10.1186/s13148-015-0155-4 92 BromerJGZhouYTaylorMBDohertyLTaylorHS
