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6.1 The safety paradox: CIDS and the second hit A key translational concern is a safety paradox: acute stroke can be followed by CIDS, which may limit secondary immune-mediated injury but also increases susceptibility to systemic infections (

10.1159/000319949 81 TangC.-X.ChenJ.ShaoK.-Q.LiuY.-H.ZhouX.-Y.MaC.-C.et al (2023)

doi: 10.1186/s12951-022-01736-8

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