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Investigations with cancer drugresistant cell lines showed that ethacrynic acid was a potent GST inhibitor, and its addition enhanced drug toxicity in resistant cell lines (Oakley et al

Barabas, K., Milner, R., Lurie, D

any infusion should have immediate access to emergency care

A.YamamotoT.SugarL

This made it possible to formulate the concept of modulators of oxidative stress in breast cancer as one of the directions of the antitumor strategy

Furthermore, these trials have limitations, including small sample sizes, wide age ranges of participants, short treatment durations, and heterogeneity in patient treatment (162)
