n-acetylcysteine mechanism acetaminophen antidote glutathione napqi Paracetamol toxicity Pharmacology 401 k Paracetamol NAPQI
Description
Superoxide dismutase (SOD) is an antioxidant enzyme produced in our bodies to neutralize a specific oxygen-derived free radical called superoxide

, 152 , 175-185, doi: Miess, H., Dankworth, B., Gouw, A

Upon cellular entry, intracellular enzymes remove the acetyl group, releasing active glutathione directly into cells

Immunotherapy was tried in 10/11 (one patient had seizure remission following temporal lobectomy and was not treated with immunotherapy)
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