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In the presence of peroxides, the selenolate form of GPX4 is oxidized to selenic acid, which is regenerated to its active form by two molecules of reduced GSH, converting lipid hydroperoxides into non-toxic lipid alcohols and generating oxidized GSH (16,9294)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 381.Boutant, M
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Nicotinamide nucleotide transhydrogenase regulates mitochondrial metabolism in NSCLC through maintenance of FeS protein function
