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K.KimH.ParkM

Convocatoria Institucional para Fortalecer la Excelencia Acadmica 2015), Programa de Mejoramiento del Profesorado (ref

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The MCD model has been demonstrated to rapidly induce NASH and fibrosis, and it has been shown to elicit strong oxidative stress and inflammatory responses, rendering it a suitable model for studying the progression from NASH to HCC
Figure 5 provides a likely scenario: The entry of TFEB into the nuclear compartment is blocked by its phosphorylation, catalyzed principally by the mechanistic target of rapamycin (mTOR), the master kinase that suppresses autophagy (Kim and Guan, 2015)
