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Animal studies have shown that when beta-3 adrenergic receptors were genetically removed, chronic AOD-9604 treatment produced no changes in weight or lipolysis, confirming the importance of this pathway

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doi: 10.1016/j.heliyon.2023.e16120

43 Serum homocysteine is less specific for B 12 deficiency, and can also be elevated in folate deficiency, vitamin B 6 deficiency, vitamin B 2 deficiency, and impaired renal function, hypothyroidism, and by certain medications

Suitable for Varied Populations: By design, AOD-9604 aims to be well-tolerated without drastically affecting blood sugar or other hormonal pathways

This provides an important tool for research into aging-related neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, and offers experimental evidence for intervention strategies in neuronal aging