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The regulatory picture varies by compound: FDA-approved peptides (semaglutide, tirzepatide) are available by prescription with full manufacturing oversight, adverse event reporting, and post-market surveillance

By way of example, phosphate-buffered saline (PBS) may be used as buffer solution

They have a proactive system for conducting annual reviews during AEP

doi: 10.3389/fcimb.2020.00341

[DOI] [PubMed] [Google Scholar] 72.Dimitriadis F., Borgmann H., Struck J.P., Salem J., Kuru T.H