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THERAPEUTIC STRATEGIES FOR WD Current pharmacological approaches Current treatment approaches aim to reduce systemic copper burden either by limiting intestinal copper absorption through zinc-induced metallothionein-mediated sequestration of copper within enterocytes or by enhancing urinary copper excretion using chelators such as D-penicillamine and trientine [4]

Inflammatory cell infiltration was also observed

Cancer 22 , 102 (2023)

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DR, Diabetic retinopathy

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