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29 On another note, both pooled and Kaplan-Meier analyses did not reveal any significant relations between mortality and the extent of tumor resection, which begs the question of whether adjuvant chemotherapy may be of help in improving the overall survival associated with this aggressive tumor
Rebouche CJ, et al

In contrast to cutaneous melanoma, clear cell sarcomas invariably arise in the deep soft tissue of the distal extremities, and 70% possess a consistent balanced translocation t(12;22)(q13;q12) that is not found in melanoma and is believed to be an early, if not primary, event in tumorigenesis

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