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PMID: 26 ChenGZhangJShengMZhangSWuQLiuLet al

Mechanisms of action of KD in neurodegeneration The classical KD is a high-fat, low-carbohydrate, and adequate-protein dietary regimen designed to mimic the metabolic effects of fasting without significant calorie restriction, thereby promoting an anabolic state [23]

The ectodomains of CRKs contain two DUF26 domains with a conserved cysteine motif, which suggests that CRKs undergo redox regulation and are key components of the ROS sensing machinery or ROS sensors 59

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Manipulation of H 2 S levels by inhibiting H 2 S synthesis or administration of H 2 S-releasing molecules revealed beneficial as well as harmful effects of H 2 S