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These medications often produce more immediate, powerful sedation but can disrupt normal sleep architecture, reduce deep sleep, and cause dependency with regular use

PMID: 35995859 ImmunityDisruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety
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ERS serves as an alert for aberrant ER function, initially aiming to adapt to changing environments and restore ER function patterns
