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Description
Elevated LPS levels compromise intestinal barrier integrity by downregulating tight junction proteins ( e.g ., ZO-1, occludin), resulting in intestinal permeability (leaky gut)
it has an intrinsic peroxidase activity and can generate reactive oxygen species by redox cycling

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This is characterized by the disruption of the cellular ferroptosis-protective mechanism

Unfortunately, the numbers have only continued to rise over the years

Regional specificity and clinical correlates of cortical GABA alterations in posttraumatic stress disorder
