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[PubMed: 11327370] 33

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GPX4 upregulation in response to BRAFi EGFRi therapy blocks therapy-induced ferroptosis and drives resistance

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Advanced disease models, including genetically stratified organoids, patient-derived iPSC lines, and age-appropriate 3D brain cultures, may offer more refined platforms to dissect these differences and identify compound-subtype associations (Sirkis et al., 2022)

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