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Medications used to treat narcolepsy primarily target EDS and/or cataplexy

The multifactorial nature of DED encompasses a number of interconnected underlying pathologies, including loss of homeostasis, instability and hyperosmolarity of the tears, and the induction and propagation of detrimental inflammatory responses in the eyes, which finally results in the development of neurosensory dysfunction and visual disruption

Devine CJJ, Somers KD, Jordan GH

Up to 4050% of patients with ALS demonstrate mild-to-moderate cognitive impairment, primarily involving executive dysfunction and impaired verbal fluency, with 15% of patients meeting criteria for frontotemporal dementia (FTD) [2]