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On the other hand, there is no doubt that in rat models of cocaine use disorder (CUD), NAC did not change cocaine reward, but effectively reduced escalation of drug intake, cocaine-seeking, and reinstatement behaviors [8, 10, 14, 19, 21, 50,51,52,53,54,55,56,57] (Table 1)

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Koepsell, 2020)

As of Week 144, the development of genotypic resistance to elvitegravir, emtricitabine, or TAF was observed in 12 of 22 subjects with evaluable resistance data from paired baseline and GENVOYA treatment-failure isolates (12 of 866 subjects [1.4%]) compared with 13 of 20 treatment-failure isolates from subjects with evaluable resistance data in the STRIBILD treatment group (13 of 867 subjects [1.5%])

In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels

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