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doi: 10.1038/nri3442 58 KoolMLambrechtBN
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When the stomach is empty, the pyloric valve opens relatively freely, allowing alcohol to pass quickly into the small intestine

Psychopharmacology (Berl) , 131 , 313320

However, individuals with absorption disorders may require significantly higher doses to achieve therapeutic levels

Methylcobalamin : A naturally occurring, active form of B12 used in some injections