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5-amino-1mq, or 5-amino-1-methylquinolinium, is a synthetic small molecule compound that targets a specific enzyme involved in metabolic regulation

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Why it matters for body composition: Smaller fat cells mean less inflammation and better insulin sensitivity, two key components for losing fat while preserving muscle

In animal obesity models, blocking NNMT cut fat mass without changing lean mass or food intake

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According to Cant et al., Cell Metabolism , increased NAD stimulates PGC-1 activity, driving mitochondrial biogenesis and substrate flexibility