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Hepatocyte growth factor decreases nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B) activation to downregulate adhesion molecules such as ICAM-1/E-selectin on the endothelial cell surface (Makondo et al., 2004

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Poultry models offer closer uric acid metabolism pathways to humans and some clinical symptom reflection, but significant limitations arise from genomic differences and specialized feeding requirements

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