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[DOI] [PubMed] [Google Scholar] 76.Lucarelli G., Galimberti M., Polchi P., Angelucci E., Baronciani D., Giardini C

In addition to MNAM and NNMTi, three new NAM analog inhibitors were reported for the treatment of MetS-related disorders in animal models: JBSNF-000088 ( JBSNF-000265 (Ruf et al., 2018), and JBSNF-000028 (Ruf et al., 2022)
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Neelakantan H, Wang HY, Vance V, et al

This resistance is often tied to changes within fat cells themselves, including the activity of a key metabolic enzyme known as NNMT
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