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Current Pharmaceutical Design, 20(7), 11211125

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E., & Akyuzc, S

Research demonstrates that BPC-157 upregulates vascular endothelial growth factor receptor-2 (VEGFR2) at both mRNA and protein levels in endothelial cells without increasing VEGF-A itself, instead sensitizing cells to existing VEGF signaling while simultaneously activating the Src-Caveolin-1-endothelial nitric oxide synthase (eNOS) pathway

These cardiovascular benefits may reduce the risk of heart disease, stroke, and other cardiovascular complications associated with obesity and metabolic dysfunction