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It works via the amylin and calcitonin receptors, enhancing satiety and reducing appetite

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While this is mechanistic and cellular rather than a human weight loss trial, it provides the biological plausibility for why correcting deficiency in real people produces improvements in how energized and metabolically active they feel

Oral LT4 is absorbed primarily in the small intestine, particularly in the jejunum and ileum, after dissolution in the stomach

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