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In the HLA-B27 rat model of colitis, administration of teduglutide at the dose of 50 g/kg/day decreased histological lesions in small and large intestine, decreased expression of the inflammatory cytokines, such as IFN- and TNF-, and improved stool consistency in comparison with control group (Alavi et al

Effects of Glucagon-Like Peptide 1 on Counterregulatory Hormone Responses, Cognitive Functions, and Insulin Secretion during Hyperinsulinemic, Stepped Hypoglycemic Clamp Experiments in Healthy Volunteers

Xu Y, et al

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Future studies should also explore the potential of emerging therapies, such as dual and triple agonists (e.g., tirzepatide and retatrutide), which have shown even greater efficacy in weight loss [20, 21]