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Allow for more efficient and complete oxidation (burning) of fats for energy

The characteristic signature of lipid modifications in lean individuals, dominated by the presence of modified octadecanoid acyl chains in phospho- and neutral lipids, is drastically shifted towards lipid peroxidation-driven accumulation of oxidized eicosanoids, suggesting significant alteration of endocrine signalling by oxidized lipids in metabolic disorders
Many individuals experience discomfort or pain in the stomach, intestines, or other parts of the digestive tract

There is also a growing body of evidence supporting similar membrane domains in prokaryotes, which may depend on sterol-analogous molecules like hopanoids (Saenz et al., 2012

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