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The current clinical evidence of intravenous glutathione for skin lightening is limited to a single study with a dubious study design and apparently flawed analysis of results, casting doubt on the drugs efficacy and reported adverse effects

Moehle M, Webber PJ, Tse T, Sukar N, Standaert D, DeSilva TM, Cowell R, West AB (2012) LRRK2 Inhibition Attenuates Microglial Inflammatory Responses

10.3389/fimmu.2019.00067 [DOI] [PMC free article] [PubMed] [Google Scholar] 168.Theiler A, Brnthaler T, Platzer W, Richtig G, Peinhaupt M, Rittchen S, et al

10a) if applied to eggs, as compared to stage L4 worms (Fig

Holdiness MR (1991) Clinical pharmacokinetics of N-acetylcysteine

Cons: lower per-capsule dose (175 mg) means you need 2-4 capsules daily, higher cost per effective dose than standard capsules, no Setria certification, sustained-release clinical data is less robust than liposomal data