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Next, a hydride transfer to NAD + occurs, which forms a Schiff base intermediate (13)

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Therefore, reducing or even preventing secondary injury-induced endogenous neuronal death after spinal cord injury and promoting early neuronal survival in the injury site and surrounding areas provide a solid foundation for the restoration of cellular functions, such as axonal regeneration, in the later stages of injury

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Most VRFs were defined as a self-reported clinical history or use of relevant medications