glutathione s-transferase polymorphisms cancer incidence and therapy transferases: substrates, inihibitors pro-drugs in and neurodegenerative diseases Glutathione S-transferasesP1 AA (105Ile) allele

Description

Apart from its main substrate H 2 O 2 , the CAT enzyme could also process other oxidative species such as O 2 - , OH, 1 O 2 , hypochlorous acid (HOCl), NO, and peroxynitrite (ONOO - )

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Results between 150250 pmol/L may indicate borderline deficiency requiring additional tests such as methylmalonic acid or homocysteine

Biomaterials, 290: 121818

[19] [21] The compounds targeted in this manner by GSTs encompass a diverse range of environmental or otherwise exogenous toxins, including chemotherapeutic agents and other drugs, pesticides, herbicides, carcinogens, and variably-derived epoxides