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A separate line of investigation, work by Pollard and colleagues, demonstrated that GHK-Cu could reverse detrimental changes in irradiated cultured human fibroblasts: cells exposed to significant radiation and then treated with GHK-Cu at very low concentrations displayed a growth pattern and growth-factor secretion profile comparable to non-irradiated control cells, including increased secretion of bFGF and VEGF

Mitochondrial-Nuclear Communication: Under conditions of metabolic stress or exercise, MOTS-c translocates to the nucleus, where it regulates the expression of nuclear genes associated with stress adaptation and homeostasis

Although nebulization of GSH and NAC as an adjuvant therapy could be beneficial in managing the early stages of COVID-19, more studies are required

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