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Genetic and chemical correction of cholesterol accumulation and impaired autophagy in hepatic and neural cells derived from Niemann-Pick type C patient-specific iPS cells

Mitochondrial fission and fusion are governed by a balance between pro-fission proteins (such as DRP1, Fis1, and MFF) and pro-fusion proteins (such as MFN1, MFN2, OPA1, MIEF1, and MIEF2), with DRP1 standing out as the key regulator of mitochondrial fission [42]

Another [NCT03104322] deployed a digital platform for IPF to track symptom progression

A potent peptidyl inhibitor of aspartic proteases is bioconversion into an open-source antimalarial compound of P

197 The antiobesity effects of phytonutrients are started by the regulation of different mechanisms or pathways such as lipid intake, absorption, and expenditure of energy, decreased lipogenesis and increasing lipolysis, and proliferation and differentiation of preadipocytes, as shown in Figure 5

Another way for HBx to induce oxidative stress is the suppression of proteins indirectly involved in the antioxidant defence, as observed in HBx-transfected HepG2 cells for the inhibition of selenoprotein P (SeP) [276] and in HBV-transgenic mice for selenium-binding protein 2 (Selenbp2) [274]