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In biological systems, hydroxyl radicals can be formed by homolytic cleavage of water using high-energy irradiation or more probably, by redox metal-catalyzed decomposition of hydrogen peroxide (reaction 7, Fenton reaction)

Therefore, across multiple experimental paradigms, our data confirm that bacterial processing of glucose promotes a decrease in lifespan as well as a reduction in health, and stress resistance

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One early study is often cited to show a lack of absorption

(2022) Nat Rev Cancer, 22: 298

8 Although relatively efficient, resistance to cisplatin, either intrinsic or acquired, during cycles of therapy is common, and overcoming tumor resistance remains the major challenge for cisplatin anticancer therapy