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2 More advanced regenerative approaches are currently under investigation

Structural and biophysical studies using NMR and small-angle X-ray scattering have demonstrated that GSH directly participates in Fe-S cluster assembly, including formation of mitochondrial Fe-S biosynthetic complexes essential for respiratory chain function 204,205

Unlike other drugs such as Mounjaro and Zepbound, which activate both GLP-1 and GIP receptors, MariTide works as a GLP-1 receptor agonist and a GIP receptor antagonist

doi: 10.1016/j.eplepsyres.2017.11.015 3

Additionally, homotaurine reduced the increase in oxidative stress biomarkers and inflammatory cytokines, such as IL-1, IL-6, and TNF- levels, caused by VPA in rats, decreased pyknosis in the prefrontal cortex, and restored the size and number of Purkinje cells in the cerebellum and regulated the dysregulated expression of GAD67 due to VPA exposure (158)