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Odh is deactivated by H 2 O 2 -induced oxidative stress in nerve terminals which has strong implications for Parkinson's disease (Tretter and Adam-Vizi, 1999

doi: 10.1016/j.tplants.2010.06.005 23 DuttaS.BasuR.PalA.KunalikaM

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The efficacy of these treatments is limited, with inconsistent impact on fibroid size and bleeding, and their use is often limited in time due to their safety profile
FEMS Yeast Res 10:10461059 Placer ZA, Cushman LL, Johnson BC (1966) Estimation of product of lipid peroxidation (malonyldialdehyde) in biochemical systems

Importantly, this dual engineering approach results in on-target and IgG subclass specific effector molecule engagement, giving rise to a toolbox that can guide design of IgG antibodies with tailored mode-of-action towards a specific target and indication
