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It was evidenced in the current study that seed extract and L-dopa have the potential to ameliorate neuronal apoptosis by regulating the PI3K/Akt signalling pathway and its consequence on the molecular targets forkhead box transcription factor and glycogen synthase kinase 3, in addition to deflecting neurodegenerative diseases like Parkinsons caused by induced neurotoxicity

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Isotretinoin side effects range from simple skin irritation to more severe symptoms, like Musculoskeletal problems.