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doi: 10.1111/bph.12309 [DOI] [PMC free article] [PubMed] [Google Scholar] 139.Wilkinson JD, Williamson EM

Additionally, ALS patient-derived induced astrocytes (iAstrocytes) were neurotoxic toward mouse motor neurons and their expression levels of disease-associated markers, including GFAP, CX43 and Ki-67, and miRNA profiles varied among patients, suggesting the astrocytes heterogeneity in ALS (Gomes et al., 2022)

25 The first line includes superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx), which encompass cytosolic SOD1 and mitochondrial matrix SOD2 that remove O 2 , catalases, and GPxs that eliminate H 2 O 2 , and certain GPxs and PRDXs that reduce lipid peroxides

10.1007/s004210050050 [DOI] [PubMed] [Google Scholar] 91.Liu C, Kurokawa R, Fujino M, Hirano Si, Sato B, Li XK

Biochanin A , an active isoflavone of Astragalus membranaceus, inhibits ferroptosis by modulating the Nrf2/system Xc-/GPX4 signalling pathway, decreasing TFR1 and ferritin levels, and relieves knee osteoarthritis (KOA) (He et al., 2023)